When running SuSE 2.4.21-99 kernel under Supermicro X5DPL motherboard, the ACPI interrupt count is astronomical.
X5DPL-iGM, X5DPL-8GM, X5DPL-TGM
Disable ACPI by adding the kernel parameter 'acpi=off' to /etc/grub.conf or upgrade the kernel to a newer version.